The corona virus is an airborne virus that can live up to three hours in the air. The virus particles are small enough to pass through HEPA filters. Most HEPA filters are 99.7% efficient in removing particles down to 0.3 micros and thereafter becomes ineffective. Covid-19 particles are 0.06 to 0.14 microns and are not effected by HEPA filters. UVC (ultraviolet germicidal) in combination of PCO (Photocatalytic Oxidation) air purifier are a promising strong candidate and most effective at breaking microorganisms such as virus, bacteria and fungi. Although, no covid-19 samples are available for testing. UVC and PCOs are highly effective at neutralizing similar virus such as MS2 (common virus/influenza). A UV wavelength of 254nm are effective in damaging microorganism DNA and in combination of PCO system serves as dual role of photocatalyst and microbial disinfection leaving a more purified air. In addition, PCO air purifiers are self-generating with less maintenance and several years of service life.